Description
The CoviDrop™ SARS-CoV-2 Targeted Proprotein Convertase Activity/Inhibition Assay Kit is a complete set of optimized buffers and reagents designed for measuring SARS-CoV-2-targeted proprotein convertase (PC) cleavage activity and inhibition using various human samples so that the functional PC activity targeting SARS-CoV-2 S1/S2 site cleavage can be identified.
- Fast: Colorimetric assay with easy-to-follow steps for convenience and speed. The entire procedure can be finished within 50 min.
- Robust: Innovative kit composition enables background signals to be extremely low and allows the assay to be simple, accurate, reliable, and consistent.
- Sensitive: The activity can be detected from as low as 2 ng of PC (ex: furin) or facilitated serine protease.
- Specific: The substrate contains entire SARS-CoV-2-S1/S2 cleavage sequence and is proven to be the same as complete trimeric form of full-length SARS-CoV-2 spike protein in PC cleavage tests. Thus, the assay is uniquely specific for detecting SARS-CoV-2-S1/S2 cleavage and is suitable for measuring inhibitory effects of various intervention against SARS-CoV-2-targeted PCs.
- Flexible: Strip-well microplate format makes the assay flexible for manual or high throughput analysis.